Brook+S.

= = Klinefelter's Syndrome

Klinefelters syndrome, which is more commonly known as XXY syndrome is when a male has an extra X chromosome. A normal male will have an XY chromosome set, but a male with klinefelters syndrome has an XXY chromosome set. Dr. Henry Klinefelter was the first to describe the symptoms this chromosome set of XXY and coined the term Klinefelter's syndrome. Scientist say that Klinefelters syndrome may be more common than the XXY syndrome holder may know. Scientist also say that 1 in 500 males have Klinefelter's syndrome and because of the mild to no symptom cases--some males that have the syndrom do not know it. Klinefelters Syndrome is not fatal, and most of the time is very easily hidden. 



Mode of Inheritance- Klinefelters Syndrome is a chromosomal error. Klinefelters Syndrome is when a male has a sex chromosome set of XXY vs the typical male chromosome set of XY. A male recieves the syndrome at birth. Below is a photo of a karyotype that displays an XXY chromosome set.


 * Symptoms: Some of the symptoms of Klinefelters syndrome vary. Although many of the males that have the syndrome do not feel any symptoms; The main symptoms are physical development, launguage development, and social development. **

//__Physical Development__//- Males with Klinefelters syndrome as an infant start to walk and talk later than other infants. he toddler stages males with the XXY chromosome set tend to have limited muscular control and tend to be taller for his age. During adolescense some males with an XXY chromosome set have limited facial hair and larger breast compared to his peers. After adolescense when a male is in his adulthood stage he will look similar to other males, but may be more suseptable to diseases most commonly found in women like breast cancer. Males with Klinefelters Syndrome are about 95-99% infertile because they produce little to no sperm.

//__Language Development-__// Some males with Klinefelters syndrome tend to have trouble learning a language. The males who have this syndrome eventually learn a language it is just a bit delayed. Along with having trouble forming a language he may also have trouble understanding something that is being said to him. After adolescense most men with Klinefelters syndrome may have dificulty reading and writing but for the most part are succesful in life.

//__Social Development-__// Males with Klinefelters syndrome tend to be well behaved through infancy to teen stage. But with this advantage comes disadvantages; he may seem less confident and quite, his hand-eye coordination may be limited and he may have a harder time making friends and may shy away from social gatherings. After adolescense and well into adulthood males will have have a normal social life with male-female relationships and friends. 

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 * Treatments- There are many treatments for Klinefelters Syndrome. || Educational Treatments- Teachers may have a specialized education program and break task down into small task so the student can better understand. ||
 * Theraputic Treatments- Many different types of counselors may be able to help strengthen his muscles and help him to learn language with ease and reduce symptoms of Klinefelters Syndrome. || Medical Treatments- Testosterone replacement treatment helps him through pubirty. (Facial Hair, Deeper Voice, Stronger Muscles, etc). Other treatments would be fertility treatments to help create an offspring. ||

Support Groups- <span style="display: block; font-size: 120%; font-family: Tahoma, Geneva, sans-serif; text-align: center;">
 * <span style="display: block; font-size: 120%; font-family: Tahoma, Geneva, sans-serif; text-align: center;">[|http://www.klinefeltersyndrome.org] || <span style="display: block; font-size: 120%; color: #12ff00; font-family: Tahoma, Geneva, sans-serif; text-align: center;">This Support Group site is unique compared to others of its kind. This support Groups website defines what exactly is Klinefelters Syndrome and also gives you stories of other people who have had the experience of dealing with Klinefelters Syndrome personally or someone who had to attened to somebody with klinefelters syndrome. ||
 * <span style="display: block; font-size: 120%; font-family: Tahoma, Geneva, sans-serif; text-align: center;">[] || <span style="display: block; font-size: 120%; color: #800080; font-family: Tahoma, Geneva, sans-serif; text-align: center;">This Support Group is also unique because it provides brochures and hotlines and local groups in which people with Klinefelters Syndrome can interact or have someone to talk to. The site also has different studies and doctors notations. ||
 * <span style="display: block; font-size: 120%; font-family: Tahoma, Geneva, sans-serif; text-align: center;">[] || <span style="display: block; font-size: 120%; color: #12ff00; font-family: Tahoma, Geneva, sans-serif; text-align: center;">This Support Group is yet again unique because you interact with other males that have been diagnosed with Klinefelters Syndrome and males can always get their feelings out about the syndrome because the person on the other end fully understands and is not there to judge. ||

<http://www.youtube.com/ watch?v=r7LoczaDrVE&eurl=http%3A%2F%2Fmrobiology%2Ewikispaces%2Ecom%2FBrook%2BS%2 E&feature=player_embedded>. || __Klinefelter's Syndrome__. 1 Apr. 2009 <http://www.nlm.nih.gov/medlineplus/ klinefelterssyndrome.html>. || __Case 2__. 1999. W. B. Saunders Company. 7 Apr. 2009 <http://omeweb2.ucdavis.edu/pmd/robbins/gen2/gen260.htm>. ||
 * <span style="display: block; font-size: 230%; color: #800080; font-family: 'Lucida Sans Unicode', 'Lucida Grande', sans-serif; text-align: center;">Work Cited ||
 * <span style="display: block; font-size: 120%; color: #12ff00; font-family: Tahoma, Geneva, sans-serif; text-align: center;">Drore. "General Genetics." Rev. of __Trisomy__. __Trisomy__. 2009. YouTube. 7 Apr. 2009
 * <span style="display: block; font-size: 120%; color: #800080; font-family: Tahoma, Geneva, sans-serif; text-align: center;">National Institutes of Health. "Klinefelter's Syndrome." __MedlinePlus:__
 * <span style="display: block; font-size: 120%; color: #12ff00; font-family: Tahoma, Geneva, sans-serif; text-align: center;">W. B. Saunders Company. "Karyotype of males with an extra X." __Genetic Disorders__