**Janelle+H.**

=**Duchenne Muscular Dystrophy **= =· Duchenne Muscular Dystrophy is also known as DMD. = = · The cause of this disease is an absence of dystrophin, a protein that helps keep muscle cells intact. = = · The start of this is usually early in a child’s years. Usually happens in early childhood, about 2-6 years. = = · The symptom of DMD is weakness. It affects the muscles of one’s hips, pelvic area, shoulders, and thighs. = = · Also the one’s calves get larger when they have DMD. = = · <span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">DMD usually affects the person's heart and their breathing muscles too. = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';"> <span style="font-size: 16pt; font-family: Symbol; mso-list: Ignore; msofareastfontfamily: Symbol; msobidifontfamily: Symbol; msolist: Ignore;">· <span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">It is rare for a person who has DMD to live past their early 30’s. = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';"> <span style="font-size: 16pt; font-family: Symbol; mso-list: Ignore; msofareastfontfamily: Symbol; msobidifontfamily: Symbol; msolist: Ignore;">· <span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">DMD is x-linked. So it only happens in the x chromosomes. = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';"> <span style="font-size: 16pt; font-family: Symbol; mso-list: Ignore; msofareastfontfamily: Symbol; msobidifontfamily: Symbol; msolist: Ignore;">· <span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">This usually only affects boys who get it from their mother. = =<span style="font-size: 16pt; font-family: 'Arial','sans-serif'; mso-spacerun: yes; msospacerun: yes;"> <span style="font-size: 16pt; font-family: Symbol; mso-list: Ignore; msofareastfontfamily: Symbol; msobidifontfamily: Symbol; msolist: Ignore;">·<span style="font-weight: normal; font-size: 16pt; color: black; line-height: 115%; font-family: 'Arial','sans-serif'; mso-themecolor: text1; msothemecolor: text1;"> W <span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">omen can be carriers of DMD but they usually don’t show any symptom. = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';"> = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">This disease causes your muscles to weaken very fast. = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';"> = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">Males are more likely to have symptoms than women. = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">The people who have DMD are not able to as much phyical activity like others. = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';"> = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">The sons of women who are carriers of DMD have a 50% chance of having it too. = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';"> = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">Also the daughter can have a 50% chance of being carriers of DMD. = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';"> = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">DMD happens in about 1 out of every 3,600 male infants. = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';"> = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">This disease usually starts in the legs and then spreds throughout the rest of the body. = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';"> = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">Duchenne Muscular Dystrophy is an inherited disorder. = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';"> = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">A female could get DMD is she was born to a father that had a damaged x chromosome. = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';"> = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">The following are some support groups of DMD: = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">1) MD Junction = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">2) Duchenne Family Support Group = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">3) FSH Society = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">4) Muscular Dystrophy Association = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">5) Parent Project Muscular Dystrophy = =<span style="font-size: 16pt; line-height: 115%; font-family: 'Arial','sans-serif';">There is no treatment for Duchenne Muscular Dystrophy. =

X-linked recessive genetic defects - how girls are affected:
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X-linked recessive genetic defects - how boys are affected:
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