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Klinefelter syndrome is also known as 47 X-X-Y Syndrome, XXY Syndrome, and XXY Trisomy. Klinefelter syndrome is a sex-linked disorder. This disorder is most common in males at birth who have one extra chromosome. Klinefelter syndrome is found in one out of every 500-1000 neborn males. Pregnancies that occur after the age of 35 are more likely to have a boy with this syndrome than younger women. Most men with this syndrome are most likely not able to father children. Although this syndrome is hard to deal with most patients have a normal productive life. There are many symptoms to this sydrome such as: The syptoms may vary and may not be cured. Not all men have the same symptoms. This disorder affects the victim physically and psychologically. Klinefelter syndrome can affect three main areas of development such as:
 * Abnormal body proportions, such as long legs, short torso, and Shoulder equal to hip size
 * Enlarged breast tissue
 * Sexual Disfunction
 * Tall Stature
 * Personality impairment


 * __Physical Development__**- newborn males with this syndrome are born with weak muscles and little strength. Most of them may sit, crawl and walk much later than other infants. Males with this syndrome tend to be taller and have less muscle control, at the age of four. As the males enter puberty they tend to make less testosterone than males who dont have Klinefelter syndrome. This problem can lead to a taller less muscular body, less body hair, broader hips, larger breasts, weaker bones, and low energy level. When males reach adulthood they take on a much different appearance than males without this condition. They are more likey to have health problems such as autoimmune disorders, breast cancer, vein diseases, osteoperosis, and tooth decay. Most males become infertile, There bodies aren't able to prodce a lot of sperm.
 * __Language Developement__**- Many boys with this syndrome are most likely to have language problems. They may learn to talk late, have trouble using their language to express thoughts, difficulty reading and they may have trouble processing what they hear. When they reach adulthood they may have trouble working in places where they have to read and write.
 * __Social Developement__**- As infants, males with this syndrome tend to be quiet and undemanding. As they reach there teen years they are more quiet and have no selfconfidence. They are also less active and more obedient and willing to help. Teens with this syndrome also have trouble with school and sports, they may have difficulty fitting in.[[image:karyotype_klinef.jpg width="307" height="289" align="right"]]

This sydrome is not inherited. It occurs randomly during early stages of fetal development. Some cells have one X chromosome and one Y chromosome and some have an extra copy of the X chromosome. The life span of Males with Klinfelter syndrome is normal.

Klinefelte syndrome is diagnosed through x-rays and through evaluations. some of the testing they do is:
 * Karyotype analysis of peripheral blood
 * checking testosterone level

It was first diagnosed In 1942 by Harry Klinefelter. It can be detected prenatally by amniocentesis and cytogenetic amniotic fluid. There are many support groups for dealing with this syndrome, one of the support groups is The American Association for Klinefelter Syndrome informationa and Support (AAKSIS) another support group is the Klinefelter Awareness Council, Also there is the Klinefelters Syndrome and Associates. They can also attend therapy for speech and physical issues


 * __Treatment__ -** it is important to start treatment as soon as possible. There are many ways of treatment such as:


 * __Educational Treatment__**- many males need special services to help them learn so the teachers may help them by slowing down the process and breaking down larger steps into smaller ones.

__**Therapeutic Options**__- They may have to go to a variety of therapists for speech, physical development, behavior, and mental health. Going to therapists may help reduce some of the symptoms such as poor muscle tone speech and self confidence.


 * __Medical Treatments__**- Testosterone replacement may be needed. The replacement may help there testosterone level, this can help them develop bigger muscles, a deep voice and grow body hair. some males can also go through fertility treament to help them father children.[[image:klinefeltersyndrome.jpg align="right"]]


 * __References-__**

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